Factors predicting exercise-induced oxygen desaturation in stable COPD

Exercise-induced oxygen desaturation in chronic obstructive pulmonary disease patients.

Interest in the causes and characteristics of chronic obstructive pulmonary disease (COPD) and its clinical manifestations has grown in the last 10 years. The range of clinical symptoms and other specific characteristics of COPD patients has led it be considered more as a syndrome than a disease, and many investigators have been motivated to define new phenotypes that reflect the particular fea...

PREDICTING WALKING-INDUCED OXYGEN DESATURATIONS IN COPD PATIENTS: A STATISTICAL MODEL A Risk Score for Walking Desaturation

Relationship between exercise desaturation and pulmonary haemodynamics in COPD patients.

Pulmonary hypertension (PH) in patients with chronic obstructive pulmonary disease (COPD) has traditionally been explained as an effect of hypoxaemia. Recently, other mechanisms, such as arterial remodelling caused by inflammation, have been suggested. The aim of this study was to investigate whether exercise-induced PH (EIPH) could occur without concurrent hypoxaemia, and whether exercise-indu...

Predictors of oxygen desaturation during submaximal exercise in 8,000 patients.

STUDY OBJECTIVES To determine predictors of oxygen desaturation during submaximal exercise in patients with various lung diseases. DESIGN AND SETTING This retrospective case series used pulmonary function laboratory results from all patients referred to a major tertiary-care center. PATIENTS AND MEASUREMENTS All patients > or = 35 years old who underwent spirometry, diffusing capacity of th...

Predictors of exercise-induced oxygen desaturation in systemic sclerosis patients with interstitial lung disease.

BACKGROUND The diffusion capacity of the lung for carbon monoxide (DLCO) is a good marker of disease severity in patients with idiopathic interstitial pneumonia, and is associated with oxygen saturation; however, little is known about DLCO in systemic sclerosis patients with interstitial lung disease. We studied potential predictors of exercise-induced oxygen desaturation in patients with syste...